*warning* advice from self taught student*
You'll get a more seasoned and experienced answer from rdrast but since it's 0348 and you're on line and he's not,
Once you make/ begin an on line edit, 5 icons become "active" in color directly above the ladder logic window, (Ladder Is all I have at this time).
From left to right they are:
1.accept pending rung edits, 2. cancel pending rung edits. 3 accept pending program edits, 4. cancel pending program edits, and lastly 5. FINALIZE all edits in program, which is a broad green and yellow arrow pointing to the right.
Hovering over any one of these once you have begun editing, and they are now in color and active, will give you the icons description.
I read that the older versions of logix used to have a "Test all Edits" but I can't speak to that.
Regards